Serra ACTIV is a powerful blend of proteolytic enzymes designed to support body’s natural inflammatory response, and promote cardiovascular health.
Inflammation is our body’s natural response to injury and infection. It is a complex biological process aimed to ward off invading pathogens and initiate the healing process. Acute inflammation is typically characterized by swelling, redness, heat, pain, and loss of function. And these signs usually subside when the underlying problem goes away. On the other, chronic inflammation may be the continuation of the acute inflammation or a prolonged low-grade form of inflammation, and it often goes unnoticed until it manifests in symptoms of a disease.
Fibrin is an insoluble protein our body produces in response to bleeding or inflammation. Under normal circumstances, excess fibrin in connective tissue is broken down by proteolytic enzymes and removed. When this process is compromised, excess fibrous material accumulates in the tissue and leads to fibrotic conditions such as arthritis.
Serra ACTIV contains various proteolytic enzymes, and it is particularly rich with its namesake serrapeptase, which is believed in alternative medicine to reduce pain and inflammation. Its proposed mode of action is supporting body’s natural mechanism for dissolving fibrin.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|Serving Size: 1 Capsule
Servings Per Container: 60
|Amount Per Serving:
|Serra ACTIV™ Blend:
|Serrapeptase (enteric Coated)
|CoActiv-8 ENZYME ENHANCER:
|**Daily Value (DV) not established
Other ingredients: Vegetarian capsule (cellulose).
Directions: Take 1 capsule daily on an empty stomach with a large glass of water. For best results, take 30-60 minutes before or 2 hours after a meal.
Available in 60 capsules per bottle.
Keep out of reach of children. If pregnant, nursing, or under medical supervision, consult your doctor. Discontinue if adverse conditions occur. Store closed in dry place; avoid excessive heat. Manufactured in a cGMP and ISO 9001:2008 facility that also processes wheat, milk, eggs, and soy.
What is systemic enzyme therapy?
Systemic enzyme therapy refers to the therapeutic use of natural enzymes to produce desired healing effects. Systemic enzymes are absorbed in the small intestine where they enter the bloodstream. Then they carry out desired benefits throughout the body.
What are proteolytic enzymes?
Proteolytic enzymes break down proteins into their building-blocks, which are called amino acids. Systemic proteolytic enzymes are responsible for breaking down accumulated protein and waste substances found in the circulatory system and connective tissue. Regular systemic proteolytic enzyme use can improve circulation.*
What is fibrin?
Fibrin is a protein-based substance that is needed to help blood coagulation, playing a substantial role in immune response. When the body responds to injury or chronic inflammation, fibrin is recruited to the damaged area to form scar tissue. Although the body is equipped with plasmin, a naturally occurring enzyme responsible for breaking down excess fibrin, plasmin levels progressively decrease as we age. This actually increases the risk for excessive, undesirable scar tissue formation in the body.
Why is it important to take Excellacor on an empty stomach?
Since most absorption occurs in the small intestine, the systemic enzymes must bypass the stomach to gain access there. If the enzymes are taken with food, they will likely begin working to break down your food within the stomach, rather than passing through to the small intestine. Taking systemic enzymes like Excellacor with food will compromise their absorption, as well as their effectiveness.
Does Excellacor have an enteric coating?
Yes, the serrapeptase in Excellacor is enterically coated. While similar systemic enzymes may have the same active ingredients, most do not utilize enteric coating. The purpose of enteric coating is to protect the enzyme from the acidic environment of the stomach. High activity level is preserved until the enzymes reach the small intestine, where absorption into the bloodstream takes place. While the enteric coating can withstand the acidic environment of the stomach, the alkaline environment of the small intestine will disintegrate the enteric coating, allowing the enzyme to be active within the bloodstream.
Do you use phthalates in your enteric coating?
No, our enteric coating does not use or contain phthalates. At AST Enzymes, we use Methacrylic Acid Copolymer (MAAC) for our enteric coating. Compared to other commonly used enteric coating agents such as Cellulose Acetate Phthalate (CAP) and Hydroxypropyl Methycellulose Phthalate (HPMCP), MAAC is the most gastro-resistant and does not carry the same risks. Additionally, MAAC is considered GRAS (Generally Recognized as Safe) by the FDA and is approved for use by the European Food Safety Authority. To learn more about enteric coating used in AST Enzymes products, please click the Compare tab.
How long should I take Excellacor before feeling results?
Since people experience varying ailments and severity of disease, the length of time to include systemic enzymes in your regimen may vary as well. As an overall guideline, it is typically recommended that new systemic enzyme users start off slow. A starter dose is generally one capsule, three times daily. After three to four days of proven tolerance, the dose can be increased to a therapeutic dose of 3 capsules, 3 times per day. At this point, results may be monitored, and dosage should be adjusted accordingly. Some consumers find their therapeutic dose between 9-15 capsules per day, while others only need 3-6. There are several factors that may affect results and required dosage, including:
- Severity of symptoms
- Time of administration (Better absorbed on an empty stomach)
- Adherence to regimen
- Nutritional state
What if I miss a dose?
Regular, consistent use of systemic enzymes will provide the best results. However, missed doses of systemic enzymes do not have serious repercussions. Although symptoms alleviated by systemic enzyme therapy may resurface, getting back on track by remembering to take your next dose will suffice. There is no need to “double up,” on one dose – and remember, systemic enzymes are best absorbed on an empty stomach.
Are there any side effects involved with Excellacor?
The use of Excellacor has not been shown to exhibit detrimental effects, neither long term nor short term. Just as dosage requirements vary, side effects may vary. Although gastrointestinal disturbances have been stated by a small percentage of new users, tolerance is maintained once the dosage is adjusted. Minor allergic reactions, like reddening of the skin, are also rare occurrences, and can be seen with extremely high doses. There are no known interactions with prescription or over the counter drugs while using systemic enzyme therapy. However, it is recommended that you consult with your physician about starting systemic enzymes, especially if you are on blood-thinning medications or if you are pregnant or nursing.
Can I take Excelacor with other systemic enzymes?
Systemic enzymes may be taken together, yielding desirable results, as long as they are taken on an empty stomach. In fact, it is often recommended that systemic enzymes be combined. Products like Excellacor and Serrapeptase often have synergistic effects when taken together. This means that the separate products work together to produce advantageous results. By combining and enhancing the activity of the enzymes, their effects on the healing process are more attainable.
Can I take Excellacor with digestive enzymes?
Although digestive and systemic enzymes are not contraindicated in terms of ingredients, they cannot be taken at the same time. The purpose of digestive enzymes is to aid in digestion of specific foods, so taking them with food is an obvious recommendation. Because systemic enzymes require an empty stomach for maximum absorption, they must be taken separately from digestive enzymes. There are no adverse interactions between systemic and digestive enzymes, but they serve different purposes and thus should be taken as directed for best results.